|
Symbol Name ID |
Clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit MGI:1858213 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypergonadotropic hypogonadism |
Hypoplasia of the ovary |
Streak ovary |
Bicornuate uterus |
Hypoplasia of the uterus |
Gonadal dysgenesis |
Premature ovarian insufficiency |
Amenorrhea |
Primary amenorrhea |
Secondary amenorrhea |
Oligomenorrhea |
| Disease(s) Associated with CLPP | |||||||||||
| Perrault syndrome |
| Mouse Phenotypes | azoospermia |
increased granulosa cell apoptosis |
decreased corpora lutea number |
abnormal granulosa cell morphology |
small ovary |
abnormal seminiferous tubule epithelium morphology |
small testis |
abnormal oogenesis |
arrest of spermatogenesis |
female infertility |
male infertility |
|
| Availability | Mouse Genotype | |||||||||||
| ClppGt(IST11134F10)Tigm/ClppGt(IST11134F10)Tigm | ||||||||||||
| ClppGt(IST13563G11)Tigm/ClppGt(IST13563G11)Tigm | ||||||||||||
| Clpptm1a(EUCOMM)Wtsi/Clpptm1a(EUCOMM)Wtsi | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools